Bio
Summary¶
Computational systems biologist and Senior Scientist in Molecular Profiling & Data Science at Regeneron, investigating mechanisms of resistance to bispecific antibody therapeutics using multimodal profiling across humanized mouse tumor models and clinical datasets.
I earned my Ph.D. in Chemical & Physical Biology from Vanderbilt University, where my work in spatial multi-omics and single-cell analysis led to a U.S. patent-pending colorectal cancer immune exclusion signature and two open-source Python packages: MILWRM for tissue domain detection and dropkick for scRNA-seq quality control. My research has appeared in Cell, Genome Research, and Cell Reports, among other peer-reviewed publications. Before Regeneron, I built production ML pipelines end to end at Decode Health and advanced diagnostics development under cGMP and CE/US-IVD standards at Asuragen. I hold a B.S. in Biomedical Engineering from The University of Texas at Austin. I’m driven by modeling and integrating high-dimensional data to map cancer initiation, progression, and the co-evolution of the tumor microenvironment.
Relevant experience in current role:
- Build scalable software and standardized pipelines for bulk and single-cell RNA-seq, TCR, and ATAC-seq in distributed computing environments
- Apply modern AI/ML to accelerate discovery—using LLM-powered named entity recognition for metadata harmonization
- Contribute to enterprise RAG-LLM initiatives - constructing and querying biomedical knowledge graphs within graph databases
- Pilot and operationalize emerging LLM tools for literature and knowledge discovery
- Regularly utilize LLMs such as GitHub Copilot to speed and scale robust code development
Education¶
Vanderbilt University
Ph.D., Chemical & Physical Biology, 2023
Dissertation: "Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors"
University of Texas at Austin
B.S., Biomedical Engineering, 2016
Awards and Leadership¶
- Graduate Student of the Year (Vanderbilt University Men's Ice Hockey - 04/2023)
- Brighter Ventures Award (Vanderbilt University School of Medicine - 06/2022)
- Dean's Award for Exceptional Achievement (Vanderbilt University School of Medicine - 07/2021)
- Lai Sulin Endowed Cancer Research Scholarship (Vanderbilt University - 04/2021)
- Russell G. Hamilton Graduate Leadership Institute Travel Grant Award (Vanderbilt University - 09/2019)
- Pre-Health Professions Certificate (The University of Texas at Austin - 05/2016)
- Sport Club Representative of the Month (The University of Texas at Austin Men's Ice Hockey - 03/2016)